So you basically like... used Winzip to split the ISO after creating it, into 4.6GB/8GB chunks (depending on the DVD size), and now want to replay them seamlessly?
I highly doubt that is possible. You can't go and just split files like that; inside of the ISO, as I'm sure you noticed, are files... so if you just randomly split a file in half, and try to play it, it isn't going to work.