FWIW, I played a decontaminated backup of Cloverfield with zero issues the other day, with PDVD 8 (first patch) and Daemon Tools.Weird. Cloverfield is VC-1 and 28 Weeks Later is AVC. So it doesn't seem to be dependant on video codec. Cloverfield doesn't have BD+, either, so, that's not it.
The only disappointment was, I expected "more" from the TrueHD track. Thought it should sound considerably better than the 448 DD track of the DVD but it doesn't (imho).
S.