not sure what problems you are having but all I did was drop the key files in the appropriate program folders, ie. key for AnyDVD (Key.AnyDVD) goes in the AnyDVD folder, same with CloneDVD, the programs check the files and do the rest, easy as that.
If you are having problems installing programs because of enforced driver signing then turn it off.
1) reboot/restart computer
2) after mem test and drive detection start hitting the F8 button BEFORE Vista is able to start up
3) select "disable enforced driver signing" it's at the bottom of the list
4) let Vista continue it's startup
As far as I can tell you only need to do this when installing programs with unsigned drivers, once installed they should run fine. You have to do this every time you start up Vista IF you going to install a program with unsigned drivers.