Yes it's possible to do.
but u need another Programm.
For Example if u wanna make a DVD-5
where part one of the Original Movie is on DVD1 and part two is on DVD2
u first have to get both DVD's on your HDD.
DVD1 in folder one
DVD2 in folder two
Than u need a programm to get both DVD's on one.
Use DVDShrink with the Option User definied Space activated.
Get the Size of both DVD's and write in it.
Than make one DVD at last it could be up to 16GB.
Now open CloneDVD, get the folder where both DVD's now one.
And Transcode it.
ITSE