After uninstall of Virtual CloneDrive I was unable to start AnyDVD (AnyDVD-autostart was disabled at that moment). There was a message about the missing VCD-drive but that was it. Solved by reinstalling AnyDVD and the (required) reboot of my PC. I could enter the settings of AnyDVD and make adjustments (like: Autostart and disable warning about missing DVD-drives). How did I get into this situation? I have a USB DVD-drive but it is not connected (only when needed). I had Virtual CloneDrive installed, so there was always a 'drive' present. But, after Windows 10-2004 update I had 'bluescreens' when rebooting or shutting down Windows. Driver issue. VCD removed, system OK. So: my PC has no DVD-drives. And I wanted to start AnyDVD... Maybe a new stuation for AnyDVD: Windows 10 does not need a (virtual) DVD-drive present. Just rightclick on a DVD.iso, choose open with Explorer and there it is, a virtual drive: "MSFT VIRTUAL DVD-ROM 1.0". It works great when AnyDVD is active! It scans the new drive at once.