I have checked with the other threads regarding vista problems and none of those solutions seem to be working for me. Here is what I'm going through. AnyDVD starts with windows and I have no problems launching it or anything like that. The problems start as soon as I insert a DVD into my drive. AnyDVD will pop up and tell me that a disk has been inserted and will open in a few moments, which it does. Then if I hit ok my computer uninstalls my DVD drive. The only way to get my DVD drive back is to reboot my computer. I have tried going into add new hardware wizard and it won't detect it. I tried going into device manager and having it scan for hardware changes, it doesn't find it. It will only find it if I reboot my computer. Here's the kicker, if the dvd is still in the drive it will uninstall the dvd drive again, but if I remove the dvd it will be fine. If I disable AnyDVD and put a dvd in the drive the dvd will play without issue.